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accession-icon GSE19626
Profiling gene expression in Vax2 knockout compared with wild type mice
  • organism-icon Mus musculus
  • sample-icon 22 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Genome 430A 2.0 Array (mouse430a2)

Description

Total RNA samples from Vax2 knockout mouse eyes (at least two biological replicates) were profiled by gene expression. As control we used total RNA from wild type eyes. The analysis was carried out at five different developmental stages: E10.5, E12.5, E16.5, P8, and P60.

Publication Title

Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye.

Sample Metadata Fields

Specimen part

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accession-icon GSE12100
hsa-mir-26b and hsa-mir-98 overexpression
  • organism-icon Homo sapiens
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

MicroRNA target prediction by expression analysis of host genes.

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE12091
Profiling gene expression in HeLa cells by hsa-mir-26b overexpression
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Description

Total RNA samples from three biological replicates in which the hsa-mir-26b was overexpressed in HeLa cells were profiled by gene expression. As negative control, we used total RNA samples from HeLa cells transfected with cel-mir-67

Publication Title

MicroRNA target prediction by expression analysis of host genes.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE12092
Profiling gene expression in HeLa cells by hsa-mir-98 overexpression
  • organism-icon Homo sapiens
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133A 2.0 Array (hgu133a2)

Description

Total RNA samples from three biological replicates in which the hsa-mir-98 was overexpressed in HeLa cells were profiled by gene expression. As negative control, we used total RNA samples from HeLa cells transfected with cel-mir-67

Publication Title

MicroRNA target prediction by expression analysis of host genes.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE73482
Gene expression patterns in allergen-driven CD4 T cell responses from human atopics with or without asthma.
  • organism-icon Homo sapiens
  • sample-icon 144 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

PBMC from house dust mite (HDM) sensitized atopics with or without asthma (or nonallergic controls) were cultured in the presence or absence of HDM extract for 24 hours.

Publication Title

Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses.

Sample Metadata Fields

Specimen part, Disease stage, Subject

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accession-icon GSE70760
Gene expression patterns in house dust mite stimulated CD4 T cells and IgG:IgE ratios
  • organism-icon Homo sapiens
  • sample-icon 89 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

PBMC from house dust mite (HDM) sensitized atopics were cultured in the presence or absence of HDM extract for 24 hours.

Publication Title

Distinguishing benign from pathologic TH2 immunity in atopic children.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE14908
Global expression profiling of CD4 T-cell responses to house dust mite allergens in human atopics and nonatopics.
  • organism-icon Homo sapiens
  • sample-icon 88 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

The aim of this study was to employ a systems-level analysis to elucidate gene expression networks operating in the CD4 T-cell responses which underpin human atopic disease.

Publication Title

A network modeling approach to analysis of the Th2 memory responses underlying human atopic disease.

Sample Metadata Fields

Time

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accession-icon GSE47655
Genomic responses in blood during acute human anaphylaxis
  • organism-icon Homo sapiens
  • sample-icon 36 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

Gene expression was profiled in peripheral blood samples collected over three time points from patients during acute anaphylaxis and from healthy controls.

Publication Title

Genomic responses during acute human anaphylaxis are characterized by upregulation of innate inflammatory gene networks.

Sample Metadata Fields

Time

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accession-icon GSE37831
In utero exposure to arsenic via drinking water impairs lung development and mucociliary clearance genes.
  • organism-icon Mus musculus
  • sample-icon 34 Downloadable Samples
  • Technology Badge Icon Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Description

In utero exposure to arsenic via drinking water increases the risk of lower respiratory tract infections during infancy and mortality from bronchiectasis in adulthood.

Publication Title

In utero exposure to arsenic alters lung development and genes related to immune and mucociliary function in mice.

Sample Metadata Fields

Sex, Age, Specimen part, Treatment

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accession-icon GSE30326
Virus-induced inflammatory gene networks underlying asthma exacerbations in vivo
  • organism-icon Homo sapiens
  • sample-icon 31 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Gene 1.0 ST Array (hugene10st)

Description

Global patterns of gene expression was profiled in nasal lavage samples obtained from asthmatic children during an acute Picornavirus-induced exacerbation and 7-14 days later.

Publication Title

No associated publication

Sample Metadata Fields

Specimen part

View Samples

refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

fund-icon Fund the CCDL

Developed by the Childhood Cancer Data Lab

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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