Affimetrix Human Gene 1.1 ST Array profiling of 763 primary medullobalstoma samples used for identification of Medullobastoma subtypes
Intertumoral Heterogeneity within Medulloblastoma Subgroups.
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups.
Specimen part
View SamplesAffymetrix Human Gene 1.1 ST Array profiling of 83 primary SHH-driven medulloblastoma samples.
No associated publication
Age, Specimen part
View SamplesAffymetrix Human Gene 1.1 ST Array profiling of 52 primary, multi-region medulloblastoma samples.
No associated publication
Sex, Age, Specimen part, Subject
View SamplesGene expression was assessed in a cohort of 40 choroid plexus tumors isolated from fresh-frozen tissue. We investigated unique expression patterns among tumor subgroups and refined the classification of choroid plexus tumors according to gene expression intensities.
Molecular characterization of choroid plexus tumors reveals novel clinically relevant subgroups.
Specimen part
View SamplesThis SuperSeries is composed of the SubSeries listed below.
Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.
Specimen part
View SamplesAffymetrix GeneChip Human Genome U133 Plus 2.0 Array profiling of 20 primary, multi-region high-grade glioma samples.
No associated publication
Sex, Age, Specimen part, Subject
View SamplesPrimary glioblastoma (GBM) cultures vary with respect to differentiation competency. We sought to identify putative transcription factors necessary for the differentiation of GBM cultures. In this dataset, we include expression data obtained from 2 human-fetal neural stem cell (HF-NS) cultures and 2 GBM stem cell (GSC) cultures. We assessed changes in gene expression from 3 timepoints during an in vitro differentiation protocol.
ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.
Specimen part, Time
View SamplesThis study revealed pathogenic role of pre-BCR-independent SYK activation in high-risk B-ALL.
Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.
Specimen part
View SamplesSUFU alterations are commonly detected in human SHH subgroup of medulloblastoma. Here we profile the gene expression of P13 wildtype and Sufu KO cerebellum, as well as Ptch1 KO MB in biological triplicate.
Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma.
Specimen part
View Samples