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accession-icon E-MEXP-3272
Transcription profiling by array of Xenopus embryos in which MyoD expression was knocked-down with antisense Morpholino Oligonucleotides
  • organism-icon Xenopus laevis
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Xenopus laevis Genome Array (xenopuslaevis)

Description

Embryos were injected with antisense Morpholino Oligonucleotides (AMOs) targetting MyoD. The transcriptional profile of these knock down embryos was compared with embryos injected with control morpholino (CMO).

Publication Title

No associated publication

Sample Metadata Fields

Age, Compound, Time

View Samples
accession-icon E-MEXP-3273
Transcription profiling ny array of Xenopus laevis animal caps overexpressing MyoD
  • organism-icon Xenopus laevis
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Xenopus laevis Genome Array (xenopuslaevis)

Description

mRNa encoding for XtMyoD was overexpressed in animal caps and the transcriptional profile of uninjected and injected animal caps was compared.

Publication Title

No associated publication

Sample Metadata Fields

Age, Specimen part, Compound, Time

View Samples
accession-icon E-MEXP-2059
Transcription profiling of Xenopus embryos from early blastula to early neurula stages
  • organism-icon Xenopus laevis
  • sample-icon 12 Downloadable Samples
  • Technology Badge Icon Affymetrix Xenopus laevis Genome Array (xenopuslaevis)

Description

Gene expression was analysed in normally developing Xenopus laevis embryos from early blastula to early neurula stages

Publication Title

Time course of gene expression in early Xenopus development

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon E-MEXP-2058
Transcription profiling by array of Xenopus embryos after treatment with dominant negative FGF receptor 1 or 4
  • organism-icon Xenopus laevis
  • sample-icon 9 Downloadable Samples
  • Technology Badge Icon Affymetrix Xenopus laevis Genome Array (xenopuslaevis)

Description

Genes regulated by the fibroblast growth factor (FGF) signalling pathway were indentified in the early development of the amphibian Xenopus laevis by comparing gene expression in control embryos and embryos in which FGF signalling was inhibited by two different dominant negative FGF receptors.

Publication Title

Characterisation of the fibroblast growth factor dependent transcriptome in early development.

Sample Metadata Fields

Age, Compound, Time

View Samples
accession-icon GSE42065
A key role for a glutathione transferase in multiple herbicide resistance in grass weeds
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

The gene encoding a protein (AmGSTF1) associated with multiple herbicide resistance (MHR) in black-grass was transgenically expressed in Arabidopsis thaliana.The goal of this study was to determine if AmGSTF1 could elicit an MHR phenotype in the transgenic host.

Publication Title

Key role for a glutathione transferase in multiple-herbicide resistance in grass weeds.

Sample Metadata Fields

Specimen part

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accession-icon GSE46958
Gene expression profiles in roots of hydroponically grown Arabidopsis treated with 0.125 mM gold
  • organism-icon Arabidopsis thaliana
  • sample-icon 6 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

Gold is widely considered to be a biologically inert element; however, it can elicit a profound biological response in plants. Plants can be exposed to significant levels of this precious metal in the environment from naturally occurring sources, as the result of mining activities or more recently resulting from the escalating use of nanoparticles in industry. In this microarray study we have investigated the gene expression response of Arabidopsis thaliana (Arabidopsis) to gold. Although the uptake of metal cations by plant transporters is well characterised, little is known about the uptake of gold, which exists in soil predominantly in a zero-valent state (Au0). We used this study to monitor the expression of candidate genes involved in metal uptake and transport. These show the down-regulation of a discreet number of genes known to be involved in the transport of copper, cadmium, nickel and iron.

Publication Title

Arabidopsis Glutathione Transferases U24 and U25 Exhibit a Range of Detoxification Activities with the Environmental Pollutant and Explosive, 2,4,6-Trinitrotoluene.

Sample Metadata Fields

Specimen part, Treatment

View Samples
accession-icon GSE25522
Larval host gene expression study in Drosophila post parasitic wasp-infection
  • organism-icon Drosophila melanogaster
  • sample-icon 4 Downloadable Samples
  • Technology Badge Icon Affymetrix Drosophila Genome 2.0 Array (drosophila2)

Description

Upon pathogenic infection, drosophila larval host mounts an immune response. Parasitic wasps inject venom that contain virulence factors during oviposition, which can elicit host immune response, and in some cases, suppress host immune responses altogether. Several microarray experiments have been performed on different classes of parasitic wasps. We wanted to compare how Ganaspis xanthopoda-infected hosts respond compared to other classes of parasitic wasps.

Publication Title

A database for the analysis of immunity genes in Drosophila: PADMA database.

Sample Metadata Fields

Time

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accession-icon GSE1071
Expression profiling of plants overexpressing transcription factor WIN1
  • organism-icon Arabidopsis thaliana
  • sample-icon 2 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis Genome Array (ag)

Description

T2 progenies of two transgenic lines overexpressing ERF transcription factor WIN1 were grown on soil in parallel under identical conditions. mRNA was extracted from pooled leaves from multiple plants of each line for the microarray experiement.

Publication Title

WIN1, a transcriptional activator of epidermal wax accumulation in Arabidopsis.

Sample Metadata Fields

No sample metadata fields

View Samples
accession-icon GSE7631
Cell-specific nitrogen responses in the Arabidopsis root
  • organism-icon Arabidopsis thaliana
  • sample-icon 83 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

The organs of multicellular species are comprised of cell types that must function together to perform specific tasks. One critical organ function is responding to internal or external change but little is known about how responses are tailored to specific cell types or coordinated among them on a global level. Here we use cellular profiling of five Arabidopsis root cell types in response to a limiting resource, nitrogen, to uncover a vast and predominantly cell-specific response that was largely undetectable using traditional methods. These methods reveal a new class of cell-specific nitrogen responses. As a proof-of-principle, we dissected one cell-specific response circuit that mediates nitrogen-induced changes in root branching from pericycle cells. Thus, cellular response profiling links gene modules to discrete functions in specific cell types.

Publication Title

Cell-specific nitrogen responses mediate developmental plasticity.

Sample Metadata Fields

Specimen part

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accession-icon GSE54049
Hit-and-run transcriptional control by bZIP1 mediates rapid nutrient signaling in Arabidopsis
  • organism-icon Arabidopsis thaliana
  • sample-icon 45 Downloadable Samples
  • Technology Badge Icon Affymetrix Arabidopsis ATH1 Genome Array (ath1121501)

Description

To identify potential transient interactions between a TF and its targets, we developed an approach that can identify primary targets based either on TF-induced regulation or TF-binding, assayed in the same samples. Our studies focused on the TF bZIP1 (BASIC LEUCINE ZIPPER 1), a central integrator of cellular and metabolic signaling.

Publication Title

Hit-and-run transcriptional control by bZIP1 mediates rapid nutrient signaling in Arabidopsis.

Sample Metadata Fields

No sample metadata fields

View Samples
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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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