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GSE36091
Mus musculus
4 Downloadable Samples
Affymetrix Mouse Genome 430 2.0 Array (mouse4302)
Description
To identify the precise molecular mechanisms that could contribute to the increase in colon carcinogenesis, microarray gene expression analysis was performed on colon RNA isolated from 5-week-old VhlF/F and VhlIE, VhlIE/Apcmin/+ and VhlF/F/Apcmin/+ mice.
Publication Title
Hypoxia-inducible factor-2α activation promotes colorectal cancer progression by dysregulating iron homeostasis.
Sample Metadata Fields
Age, Specimen part
View Samples- Mus musculus
- 4 Downloadable Samples
- Affymetrix Mouse Gene 2.1 ST Array (mogene21st)
Description
To investigate the detailed molecular mechanisms for the regulatory role of Dmt1 in colon tumorigenesis, microarray gene expression analysis was performed on normal and tumor colon tissue RNA isolated from 3-month-old CDX2; Dmt1+/+/ApcF/+and CDX2; Dmt1F/F/ApcF/+ mice.
Publication Title
Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis.
Sample Metadata Fields
Age
View Samples- Mus musculus
- 4 Downloadable Samples
- Affymetrix Mouse Gene 2.1 ST Array (mogene21st)
Description
To investigate the detailed molecular mechanisms for the regulatory role of Nik in colitis, microarray gene expression analysis was performed on colon tissue RNA isolated from 3-month-old untreated control and DSS treated Nik+/+ and NikIE mice.
Publication Title
Intestinal non-canonical NFκB signaling shapes the local and systemic immune response.
Sample Metadata Fields
Age
View Samples- Mus musculus
- 2 Downloadable Samples
- Affymetrix Mouse Genome 430 2.0 Array (mouse4302)
Description
To investigate the detailed molecular mechanisms for the regulatory role of HIF-2 in experimental colitis, microarray gene expression analysis was performed on colon RNA isolated from 6- to 8-week-old Hif-2F/F, Hif-2lIE mice treated with 3%DSS for 3 days.
Publication Title
Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice.
Sample Metadata Fields
Age, Specimen part
View Samples- Mus musculus
- 2 Downloadable Samples
- Affymetrix Mouse Gene 1.1 ST Array (mogene11st)
Description
To investigate the detailed molecular mechanisms for the regulatory role of HIF-1 in colon, microarray gene expression analysis was performed on colon RNA isolated from 6- to 8-week-old Hif-1+/+, Hif-1LSL/LSL mice.
Publication Title
Activation of HIF-1α does not increase intestinal tumorigenesis.
Sample Metadata Fields
Age, Specimen part
View Samples