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accession-icon GSE34166
mRNA expression profiling of ERCP biliary brushings of malignant biliary strictures
  • organism-icon Homo sapiens
  • sample-icon 10 Downloadable Samples
  • Technology Badge Icon Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)

Description

Identification of differential gene expression uging endoscopic biliary brushings

Publication Title

Whole genome RNA expression profiling of endoscopic biliary brushings provides data suitable for biomarker discovery in cholangiocarcinoma.

Sample Metadata Fields

Sex, Specimen part

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accession-icon GSE73464
Diagnosis of Kawasaki Disease in children using host RNA expression
  • organism-icon Homo sapiens
  • sample-icon 839 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip, Illumina HumanHT-12 V3.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature.

Sample Metadata Fields

Sex

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accession-icon GSE72829
Diagnosis of childhood bacterial and viral infection using host RNA expression
  • organism-icon Homo sapiens
  • sample-icon 202 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip, Illumina HumanRef-8 v3.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children.

Sample Metadata Fields

Sex, Specimen part, Disease, Disease stage

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accession-icon GSE39941
Genome wide transcriptional profiling of HIV positive and negative children with active tuberculosis, latent TB infection and other diseases
  • organism-icon Homo sapiens
  • sample-icon 491 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

Diagnosis of childhood tuberculosis and host RNA expression in Africa.

Sample Metadata Fields

Disease

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accession-icon GSE73461
Diagnosis of Kawasaki Disease in children using host RNA expression [Discovery_Dataset]
  • organism-icon Homo sapiens
  • sample-icon 459 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip, Illumina HumanHT-12 V4.0 expression beadchip

Description

Genome-wide analysis of transcriptional profiles in children <17 years of age with inflammatory diseases, bacterial or viral infections or with clinical features suggestive of infection.

Publication Title

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature.

Sample Metadata Fields

Sex

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accession-icon GSE111368
Progression of whole blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in patients with severe influenza
  • organism-icon Homo sapiens
  • sample-icon 359 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip

Description

Transcriptional profiles are increasingly used to investigate the severity, subtype and pathogenesis of disease. We now describe whole blood RNA signatures and local and systemic immune mediator levels in a large cohort of adults hospitalised with influenza from which extensive clinical and investigational data was obtained. Signatures reflecting interferon-related antiviral pathways were common up to day 4 of symptoms in cases not requiring mechanical ventilatory support; in those needing mechanical ventilation, an inflammatory, activated neutrophil and cell stress/death (bacterial) pattern was seen, even early after disease onset. Identifiable bacterial co-infection was not necessary for this bacterial signature but could enhance its development while attenuating the early viral signature. Our findings emphasise the importance of timing and severity in the interpretation of transcriptomic profiles and soluble mediator levels, and identify specific patterns of immune activation that may enable the development of novel diagnostics and therapeutics

Publication Title

Progression of whole-blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in severe influenza.

Sample Metadata Fields

Sex, Age, Race, Subject, Time

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accession-icon GSE39940
Genome wide transcriptional profiling of HIV positive and negative children with active tuberculosis, latent TB infection and other diseases from South Africa and Malawi
  • organism-icon Homo sapiens
  • sample-icon 334 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip

Description

The study aimed to define transcriptional signatures for detection of active TB (TB) compared to latent TB infection (LTBI) as well as to other diseases (OD) with similar clinical phenotypes in patients with and without HIV in two African paediatric populations.

Publication Title

Diagnosis of childhood tuberculosis and host RNA expression in Africa.

Sample Metadata Fields

Disease

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accession-icon GSE72809
Diagnosis of childhood bacterial and viral infection using host RNA expression [Discovery set]
  • organism-icon Homo sapiens
  • sample-icon 39 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V4.0 expression beadchip, Illumina HumanRef-8 v3.0 expression beadchip

Description

Genome-wide analysis of transcriptional profiles in children <17 years of age with bacterial or viral infections or with clinical features suggestive of infection.

Publication Title

Diagnostic Test Accuracy of a 2-Transcript Host RNA Signature for Discriminating Bacterial vs Viral Infection in Febrile Children.

Sample Metadata Fields

Sex, Specimen part

View Samples
accession-icon GSE73463
Diagnosis of Kawasaki Disease in children using host RNA expression [Validation_HT12V4_Dataset]
  • organism-icon Homo sapiens
  • sample-icon 233 Downloadable Samples
  • Technology Badge IconIllumina HumanHT-12 V3.0 expression beadchip, Illumina HumanHT-12 V4.0 expression beadchip

Description

Genome-wide analysis of transcriptional profiles in children <17 years of age with inflammatory diseases, bacterial or viral infections or with clinical features suggestive of infection.

Publication Title

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature.

Sample Metadata Fields

Sex

View Samples
accession-icon GSE76227
Expression data of bronchial biopsies and epithelial brushing from Unbiased BIOmarkers in Prediction of REspiratory Disease outcomes (U-BIOPRED) Project
  • organism-icon Homo sapiens
  • sample-icon 187 Downloadable Samples
  • Technology Badge Icon Affymetrix HT HG-U133+ PM Array Plate (hthgu133pluspm)

Description

This SuperSeries is composed of the SubSeries listed below.

Publication Title

No associated publication

Sample Metadata Fields

Sex, Age, Specimen part, Disease

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