GDF11 treatment leads to bone loss in mice and strongly stimulates RANKL-induced osteoclastogenesis of bone marrowderived macrophages (BMMs) in vitro.
GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation.
Specimen part, Treatment
View SamplesTo obtain and analyze early retinal changes at molecular level at 24h after ipsilateral intraorbital nerve radiation injury by gamma knife surgery
Retinal whole genome microarray analysis and early morphological changes in the optic nerves of monkeys after an intraorbital nerve irradiated injury.
Specimen part, Treatment
View SamplesTuberculosis (TB) is the ninth leading cause of death worldwide and the leading cause from a single infectious agent, ranking above HIV/AIDS.Although considerable advances have been achieved in recent years, the genetic and molecular mechanisms underlying this disease remain largely unclear.
No associated publication
Specimen part, Disease stage
View SamplesAnalysis of spleen samples taken throughout the acute phase of infection from mice infected with virulent P. chabaudi CB strain
Transcriptome analysis of blood and spleen in virulent and avirulent mouse malaria infection.
Sex, Specimen part, Time
View SamplesRodent malaria parasite RNA hybridized on Illumina Mouse WG-6 v2.0 Expression BeadChip
Transcriptome analysis of blood and spleen in virulent and avirulent mouse malaria infection.
Sex, Specimen part
View SamplesRNA-sequencings of TSPY1-overexpressed A549 and HepG2 cells were performed to systematically explore the signaling pathways in which TSPY1 is involved during tumor progression.
No associated publication
Sex, Age, Specimen part, Cell line, Treatment
View SamplesThe xylose fermentation capability of an industrainl Saccharomyces cerevisiae strain was enhanced by adaptive evolution. Eight homozygots were generated by tetrads dissection.
Comparative transcriptomes reveal novel evolutionary strategies adopted by Saccharomyces cerevisiae with improved xylose utilization capability.
No sample metadata fields
View SamplesThe molecular basis for glucose and xylose fermentation by industrial Saccharomyces cerevisiae is of interest to promote bioethanol production
Transcriptomes of a xylose-utilizing industrial flocculating Saccharomyces cerevisiae strain cultured in media containing different sugar sources.
No sample metadata fields
View SamplesPlant microRNAs (miRNAs) act as negative regulators of gene expression by slicing target transcripts or inhibiting the translation, and a number of miRNAs play important roles in development. In order to investigate the potential function of miRNAs during male gametogenesis in rice, we obtained both gene and small RNA expression profiles by combining Affymetrix microarray and high-throughput sequencing technologies. In genome-scale, we compared arrays and sRNA-Seq datasets in different stages/organs of rice by applying computational and statistical approaches.
MicroRNA profiles and their control of male gametophyte development in rice.
Specimen part
View SamplesAdipogenesis participates in many physiological and pathological processes such as obesity and diabetes, and is regulated by a series of precise molecular events. However, the molecules involved in this regulation have not been fully characterized.
No associated publication
Sex, Specimen part
View Samples