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Gallus gallus
7 Downloadable Samples
Illumina HiSeq 2000
Description
The goal of this study is to obtain the transcriptomes of chicken magnum in different natural developmental stages. There are totally five stages researched in this study and they are named D1, D2, D3, D4 and L. D1 to D4 are the abbreviations of developmental stage 1 to developmental stage 4 and L means laying stage. D1 refers to the lag phase (about 7 weeks old) in which the magnum has very slight change; D2 refers to the early proliferation phase (about 13 weeks old); D3 refers to the late proliferation phase (about 16 weeks old); D4 refers to the early differentiation phase (about 17 weeks old).
Publication Title
No associated publication
Sample Metadata Fields
Age
View Samples- Gallus gallus
- 6 Downloadable Samples
- Illumina HiSeq 2500
Description
In the experiment, we took a chinese chicken with different body weights at 300 days as the research subjects. The chickens were divided into fast- and slow-growing groups (high body weight and low body weight). We selected leg muscles after slaughtering and used then for RNA-seq. Finally, we screened differentially expressed genes and the corresponding enriched pathways related to growth through a bioinformatics analysis. The results provide a theoretical foundation for revealing the molecular mechanism of the growth for chickens and improving the production performance of the Jinghai yellow chicken.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part
View Samples- Sus scrofa
- 6 Downloadable Samples
- Illumina HiSeq 2000
Description
Backfat thickness traits are strongly associated with meat quality, fattening efficiency, reproductive performance, and immunity in pigs. Fat storage and fatty acid synthesis mainly occur in adipose tissue. Therefore, we used a high-throughput massively parallel sequencing approach to identify transcriptomes in adipose tissue from three full-sibling pairs of pigs with opposite (high and low) backfat thickness phenotypes.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Age, Specimen part
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SRP174379- Ovis aries
- 6 Downloadable Samples
- Illumina HiSeq 2000
Description
In order to indentify and screen the differentially expressed genes in meat sheep mammary tissues between healthy and naturally infected with clinical mastitis
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part
View Samples SRP160045- Sus scrofa
- 4 Downloadable Samples
- Illumina HiSeq 2000
Description
The regulation of lipid metabolism takes place in the principal organs as liver. In this study, we have used massive parallel high-throughput sequencing technologies to the porcine liver tissue transcriptome architecture in two pairs full-sibs Landrace pigs showing extreme phenotypes for backfat thickness of live.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part
View Samples- Mus musculus
- 3 Downloadable Samples
- Illumina HiSeq 2000
Description
Metabolic disorders, especially obesity and diabetes, become the most important public health concern in worldwide. The pathophysiology seems to be largely attributable to endoplasmic reticulum (ER) stress, inflammation and cytokines resistance (e.g. leptin resistance and insulin resistance) in adipose tissue. Therefore, dynamic improvement of these disorders in adipose tissue provides an effective therapeutic strategy to alleviate severe systemic metabolic disorders. In this study, we investigated the effects of leptin on autophagy and inflammation of adipose tissue. We show that leptin alleviates ER stress-induced inflammation through the Atf4/Atg5-mediated autophagy in mice adipocytes. Thus, our study has revealed the mechanistic link between leptin, autophagy and ER stress, providing novel insights into the pharmacologically therapeutic target for obesity and inflammation.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Age, Specimen part, Cell line
View Samples- Danio rerio
- 2 Downloadable Samples
- Illumina HiSeq 2000
Description
The effect of oligosaccharides on zebrafish genes
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part
View Samples SRP096928- Mus musculus
- 1 Downloadable Sample
- Illumina HiSeq 4000
Description
No description.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part
View Samples- Sus scrofa
- 1 Downloadable Sample
- Illumina HiSeq 2000
Description
The previous study found that the expression level of miR-215 in the small intestine of E. coli F18-sensitive group was significantly higher than that of the resistant group, which suggested that miR-215 may be an important miRNA regulating E. coli resistance. Therefore, this study performed a transcriptome sequencing analysis of miR-215-interfered cell lines in order to explore possible miR-215 target genes and key regulatory genes or signaling pathways, and further analyze the molecular mechanism of weaned pigs'' resistance to E.coli F18 diarrhea.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Cell line
View Samples- Sus scrofa
- 1 Downloadable Sample
- Illumina HiSeq 2000
Description
The previous study found that the expression level of miR-215 in the small intestine of E. coli F18-sensitive group was significantly higher than that of the resistant group, which suggested that miR-215 may be an important miRNA regulating E. coli resistance. Therefore, this study performed a transcriptome sequencing analysis of miR-215-interfered cell lines in order to explore possible miR-215 target genes and key regulatory genes or signaling pathways, and further analyze the molecular mechanism of weaned pigs'' resistance to E.coli F18 diarrhea.
Publication Title
No associated publication
Sample Metadata Fields
Sex, Specimen part, Disease, Cell line
View Samples